Aug 22, 2018 · “Mylan has a strong history of leading the way in creating important access to generic medicines, and we’re excited to continue that tradition by offering the first generic to Adcirca Tablets,” Heather Bresch, CEO of Mylan, said in a press release.. “Mylan offers more than 650 products in the U.S., and the addition of Tadalafil Tablets strengthens our …

Mar 27, 2024 · The now-approved treatment is expected to be available for dispensing by select U.S. specialty pharmacies by the end of April, according to Merck, which has owned the rights to the biologic therapy since acquiring prior developer Acceleron Pharma in 2021. Winrevair specifically is intended to enhance exercise capacity, improve World Health Organization (WHO) functional class, and reduce the ...

Dec 20, 2024 · In PAH, high blood pressure in the blood vessels that carry blood from the heart to the lungs results in symptoms like shortness of breath, fatigue, and chest pain. The disease can make even simple activities, like walking or climbing stairs, increasingly difficult and negatively impacts patients’ quality of life.

Jul 8, 2019 · An estimated right ventricular systolic pressure (eRVSP) — a measure of the pressure inside the artery that supplies blood to the lungs (pulmonary artery) — greater than 30.0 mmHg is related to an increased risk of mortality in patients with pulmonary hypertension (PH), according to a new Australian study.

Dec 16, 2024 · An oxygen-sensing protein called hypoxia-inducible factor-1alpha, or HIF-1alpha, may contribute to worsening pulmonary arterial hypertension (PAH) and is a possible therapeutic target for people with this rare type of pulmonary hypertension, a study by …

Dec 18, 2024 · The researchers noted that these three genes are involved in some of the same biological pathways as the five metabolites. Among shared biological processes were immune response regulation and inflammation (kynurenine, tryptophan, and MAPK6), as well as cell growth (spermine and SLC7A11).. The scientists stressed that this study was based mainly on data from a small number of patients, so ...

Nov 27, 2024 · These top-line findings in the ongoing ZENITH trial (NCT04896008), testing the Merck treatment against a placebo while on background therapy, led an independent data monitoring committee to recommend the trial be stopped early. All enrolled patients now are invited to enter the open-label SOTERIA (NCT04796337) extension study and be …

Nov 22, 2024 · The study, “ Expression and Diagnostic Value of miR-3591-5p in Patients with Congenital Heart Disease-Associated Pulmonary Arterial Hypertension,” was published in Lung. PAH is marked by high blood pressure in the vessels that carry blood through the lungs. People with congenital heart disease (CHD), a broad category that encompasses problems with heart structure or function from birth ...

Oct 7, 2024 · Investigating the role of selenium in people with PAH. PAH is a type of pulmonary hypertension (PH) caused by the narrowing of the pulmonary arteries, which are the blood vessels that supply the lungs. This leads to high blood pressure and may cause right heart failure, the most common cause of death among PAH patients.

5 days ago · Right heart size differs between men and women with PAH: Study. Men with pulmonary arterial hypertension (PAH) have a larger right heart size and worse survival rates than women, independent of body size and functional status, a study reports.