The TCR is a member of the immunoglobulin superfamily, a large group of proteins involved in binding, recognition, and adhesion; the family is named after antibodies (also called immunoglobulins).

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The TCR (T-cell receptor) is a complex of integral membrane proteins that participate in the activation of T-cells in response to an antigen. Stimulation of TCR is triggered by MHC (major histocompatibility …

T cell receptor (TCR) therapy is a new type of treatment that uses your own immune cells to fight cancer. It is a promising therapy for some types of cancer, including soft tissue sarcoma.

Dec 13, 2021 · Normal T cell development in the thymus undergoes a major developmental checkpoint in which T cell receptor (TCR) signaling is involved.

Welcome to the T cell receptor (TCR) structural repertoire database. Here we provide an easy-to-use interface to view all experimentally determined structures of T cell receptors and their complexes.

3 days ago · T Cell Receptor (TCR) activation promotes a number of signaling cascades that ultimately determine cell fate through regulating cytokine production, cell survival, proliferation, and differentiation.

T cell receptor (TCR) is a specific recognition structure on the surface of T cells, which can be called "radar" of T cells. TCR is mainly composed of α and β chains, and each chain contains variable …

Jan 24, 2020 · In this review, we examine the molecular basis for TCR activation in light of the recently determined cryoEM structure of a complete TCR-CD3 complex. This structure provides an …

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