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  1. Tirzepatide as Compared with Semaglutide for the Treatment of …

    May 11, 2025 · Tirzepatide and semaglutide are highly effective medications for obesity management. The efficacy and safety of tirzepatide as compared with semaglutide in adults …

  2. The New England Journal of Medicine | Research & Review Articles …

    The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of ...

  3. New England Journal of Medicine

    The New England Journal of Medicine publishes high-quality medical research, reviews, and opinions to advance medical science and improve patient care.

  4. Tezepelumab in Adults with Severe Chronic Rhinosinusitis with …

    Mar 1, 2025 · Treatment with tezepelumab has been effective for sinonasal symptoms in patients with severe, uncontrolled asthma and a history of chronic rhinosinusitis with nasal polyps, but …

  5. Zongertinib in Previously Treated - The New England Journal of …

    Apr 28, 2025 · Innovative oral targeted therapies are warranted for patients with human epidermal growth factor receptor 2 (HER2)–mutant non–small-cell lung cancer (NSCLC). Zongertinib is …

  6. Lepodisiran - The New England Journal of Medicine

    Mar 30, 2025 · Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small …

  7. Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

    May 15, 2025 · Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with …

  8. Recently Published | The New England Journal of Medicine

    5 days ago · Explore this issue of The New England Journal of Medicine (Vol. 0 No. 0).

  9. Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis

    Apr 23, 2025 · In bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression. Brensocatib, an oral, reversible inhibitor of dipeptidyl …

  10. Phase 3 Trial of Semaglutide in Metabolic Dysfunction–Associated ...

    Apr 30, 2025 · Semaglutide, a glucagon-like peptide-1 receptor agonist, is a candidate for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). In this ongoing phase …

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