Combined checkpoint inhibition therapy targeting the programmed cell death 1 (PD-L1) and cytotoxic T-lymphocyte associated protein 4 pathways has been a successful approach in the treatment of ...

Rhinosporidiosis is a chronic granulomatous disease mainly affecting the nasal cavity and nasopharynx. It is an endemic disease in South India. Its incidence in the UK is very low. In this case report ...

Post-cholecystectomy clip migration (PCCM) is a rare but recognised complication that can occur early or years after surgery. Given its potential to cause biliary obstruction, PCCM should be ...

A male refugee from the Middle East was diagnosed with pulmonary tuberculosis and Pott’s disease with paravertebral abscess. After starting the standard regimen, the sputum culture converted to ...

Sheehan’s syndrome (SS) is ischaemic necrosis of the pituitary gland due to massive postpartum haemorrhage. The clinical manifestations may vary from subtle to life-threatening and may present ...

Penetrating glass injuries in the facial region represent a very rare and complex variety of trauma. Cases of glass foreign bodies in the orbital tissue or the eyeball have been reported. Scattered ...

This case report presents a woman in her 20s with VACTERL association who presented with acute on chronic 10-year pelvic pain and haematometra. Initially, diagnostic imaging suspected a didelphic ...

Tuberculosis (TB) is one of the most prevalent diseases in the Indian subcontinent. Ocular TB presenting as iris mass is rare; furthermore, invasion of anterior segment without choroidal invasion is ...

A 53-year-old man admitted to the critical care secondary to respiratory failure due to COVID-19 developed agitation and global hypotonia. Brain MRI revealed bilateral hyperintense lesions throughout ...

A 50-year-old man presented with a 2-day history of bilateral lower extremity cramping and dark urine. The patient was found to have a creatine phosphokinase (CPK) elevated of up to 2306 U/L, a serum ...

Alveolar rhabdomyosarcoma (ARMS) has a predilection for the peripheral extremities, and brain metastases are rare, with only a few cases reported after the initial diagnosis. We present a 22-year-old ...

A case of a patient in her 30s with sickle cell anaemia who developed multiorgan failure and Acute Respiratory Distress Syndrome(ARDS) from acute chest syndrome (ACS) despite a simple red blood cell ...