Jannik Sinner will launch his Australian Open title defence under a stubborn doping cloud but the whiff of scandal may do little to halt the Italian juggernaut. Sinner remains the man to beat at Melbourne Park even as doping officials seek a two-year ban for the world number one for failing two drugs tests last March.

2025 Australian Open men’s prediction 1: Novak Djokovic to win E/W - 5/1 BetVictor It’s been 49 years since an Australian won the Australian Open, but Alex de Minaur looks to have a fighting chance of ending that run this year.

Ten-time Australian Open champion Novak Djokovic faces a potentially tricky opener against wildcard Nishesh Basavareddy, a rising American talent. The Serb, determined to reclaim the title he last won in 2023, could meet third-seeded Carlos Alcaraz in a blockbuster quarterfinal clash.