The next set of discoveries between the Neher and Sakmann labs arrived in a set of three: whole-cell, inside-out, and outside-out patch clamp recordings. Alain Marty, another postdoctoral researcher ...

View Full Profile. Learn about our Editorial Policies. “This whole-cell patch method is really the gold standard for looking at synaptic and other events that make a neuron compute,” says Ed Boyden, a ...

Sensorimotor integration, whole-cell patch clamp and imaging in behaving animals, optogenetics, neuromechanics, locomotion. Micro/nanotechnology, single-molecule detection, genomic technology, DNA/RNA ...

Alongside undeniable technical advances such as whole-cell patch-clamp recording and the retinal slice preparation, a major determinant of this recent progress is the conceptual foundation laid ...

We employ a multi-pronged approach which includes in vivo whole-cell patch clamp recordings, imaging, quantitative measurement of behavior, biomechanics, and computation.