Describes the nature of a clinical study. Types include: Observational study — observes people and measures outcomes without affecting results. Interventional study (clinical trial) — studies new ...

Aortic stenosis is the most common valvular lesion in patients above the age of 65. The etiology, presentation, and management of aortic stenosis differs in the elderly compared to younger ...

Aortic stenosis is a serious heart valve condition characterized by narrowing and stiffening of the aortic valve, restricting blood flow from the heart to the body. This forces the heart to work ...

Adding Farxiga (dapagliflozin) to standard care significantly reduced the risk of death or worsening heart failure in older patients with severe aortic stenosis following transcatheter aortic-valve ...

All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the ...

The timing of aortic valve replacement (AVR) in asymptomatic patients with severe aortic stenosis has been debated for several decades. Based on observational data and expert opinion, international ...

They then shut tightly until the next heartbeat. If you have aortic regurgitation, the flaps around your aortic valve — the valve that pumps blood to your heart — don’t close fully.

For over a decade, the McGill University Health Centre (MUHC) has been at the forefront of aortic valve innovation, advancing how we treat cardiac patients through minimally invasive approaches. That ...

Instead, the cause is ulcers formed due to wear of the aortic wall which is caused by atherosclerosis. Aortic stenosis: With this condition, the aortic valve doesn’t open completely when it should, ...

The extent of cardiac damage has been shown to be associated with increased mortality, repeat hospitalization, and decreased quality of life after aortic valve replacement (AVR). However, the ...

Mild or moderate calcific aortic stenosis is likely to progress with increasing deposition of calcium on the aortic cusps. The rate of progression can be quite variable, with the occasional ...

This procedure may be needed if your aortic valve is working poorly. This may happen if you have aortic valve stenosis or aortic valve regurgitation. In aortic stenosis, the valve can't open fully.