San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers ‘ season finale versus the ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped ...

Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, but he didn't damage the ACL in his left knee during Sunday's loss at Arizona, Matt Barrows of The ...

Guerendo won't return to Sunday's game at Arizona due to knee and ankle injuries. Guerendo had his left leg twisted under him on his second carry of the game, and his teammates quickly motioned to the ...

San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated: ...

The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?

The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, ...

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the ...

RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to Week 17’s game vs. the Lions ...