Gascón is the first openly trans person to be nominated for an acting Oscar, though Elliot Page was nominated for 2007's "Juno" before coming out as trans in 2020.After blazing a trail for LGBTQ representation throughout the 2025 awards season,

Karla Sofía Gascón was nominated for best actress for her performance in the Netflix musical/crime drama about a drug lord seeking gender reassignment surgery. As trans rights have become a highly politicized issue in the US,

Emilia Pérez' star Karla Sofía Gascón has become the first openly transgender actor to be nominated for an Academy Award.