After everything is positioned on the slide, save your changes to ensure the work is not lost. You can overlay one or even multiple images using the same process in PowerPoint.

How to Create an Image Map in Microsoft Word or PowerPoint. ... With a bit of work and some carefully-positioned shapes, ... the process is the same in both.

In PowerPoint 2007, click the Office button and choose Save As. In the Save As dialog box, locate a folder for saving the new image file. Give the new image a name.