Whole-cell recordings and outside-out patch-clamp techniques were employed to analyze ion transport properties. GluA2-containing AMPARs exhibited a range of calcium permeability levels ...

It provides in-depth descriptions of various patch-clamp recording methods, including single-channel, whole-cell, perforated patch, and in vivo approaches. In addition to patch-clamp techniques, the ...

However, repair mechanisms not only defend against external threats; they also play a crucial role in helping cells survive the challenges they face in their daily fight for survival. Scientists ...

How cells repair their power plants Date: April 4, 2025 Source: Heinrich-Heine University Duesseldorf Summary: Damage to the mitochondria, the 'power plants' of the cells, contributes to many ...

Damage to the mitochondria, the “power plants” of the cells, contributes to many diseases. Researchers from Heinrich Heine University Düsseldorf (HHU) and the University of Cologne led by HHU ...

DNA repair mechanisms are crucial for the survival and growth of cells. Through a comprehensive analysis, a research team at ETH Zurich has identified numerous redundancies between the genes involved ...

Such damage also speeds up the aging process. However, the cells are normally capable of identifying such damage and reacting. Scientists from University Hospital Düsseldorf and HHU have—in ...

Here, we explored how NMDARs signal in tLTD. We found that, regardless of frequency, L5 PC→PC tLTD relies on the non-ionotropic preNMDAR signaling pathway mediated by JNK2, which helps to resolve the ...

However, repair mechanisms not only defend against external threats; they also play a crucial role in helping cells survive the challenges they face in their daily fight for survival. Scientists ...