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Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune ...

One chemistry tweak made mRNA vaccines dramatically safer and more effective—unlocking new potential for fighting disease.

By Heather Norman-Burgdolf University of Kentucky Ticks are bad news in general, but the lone star tick brings an extra problem: it can leave behind a sugar molecule called alpha-gal that may flip ...

When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and chronic inflammation. A new chemical tool developed at UC Riverside ...

This study analyzes the relationship between vancomycin trough concentration and treatment outcome of infection by drug-resistant Gram-positive bacteria in children using real-world data, as well as ...

Rescued by fat bubbles: Scientists treat rare genetic disease with designer molecule by Miriam Fauzia edited by Sadie Harley, reviewed by Andrew Zinin Editors' notes ...

A stroke drug called GAI-17 protected mouse brains even six hours after damage began—and may one day help fight Alzheimer’s too, without harmful side effects.

The incidence of recurrent Clostridioides difficile infection was lower among at-risk patients on antibiotics for other indications who received oral vancomycin vs. placebo, according to study ...

We identified a promising RNA molecule that could be therapeutically targeted to treat patients with kidney diseases, such as chronic kidney disease. Q: What are the next steps?

A bacterially produced molecule circulates in the bloodstream and increases the risk of cardiovascular disease by hijacking immune-cell signalling.