The rare toad species produces a venom known as 5-MeO-DMT, an extremely powerful natural psychedelic that's around four to six times more potent than its better-known cousin DMT (dimethyltryptamine).

Increased interest in Bufo alvarius toad venom — derived from the animal’s defense secretions and containing the psychoactive compound 5-MeO-DMT — is seeing toad populations routinely ...

Former boxing champ Mike Tyson is a fan of the psychedelic toad venom from the Bufo alvarius amphibian, and will soon be producing a line of cannabis inspired by his experiences with it.

Venom from the glands of the Sonoran Desert toad, dried into crystals, and smoked in a pipe was the process; “Mother Nature’s best brew” was Sandoval’s more abbreviated pitch.

The venom is produced during the toad’s defense secretions and contains 5-MeO-DMT, a psychoactive compound. Mike Tyson is interviewed on "Jimmy Kimmel Live." (ABC via Getty Images) MIKE TYSON ...