Failure of a gene-reading quality-control mechanism called Integrator leaves cells littered with abnormal RNA strands that ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Phase-contrast microscopy is entirely label free ... As a test, they compared healthy fibroblast cells, the key component of animal tissue, and malignant fibrosarcoma cells, cancerous cells ...

This award will support research led by Suresh Thallapuranam, in collaboration with Kyle Quinn and Narasimhan Rajaram from the Department of Biomedical Engineering, along with Jingyi Chen from the ...

5 Microscopy-based karyotyping methods such ... such as epidermal growth factor receptor (EGFR) and fibroblast growth factor receptor 1 (FGFR1), are validated drug targets for therapeutic ...

Researchers in Nikolaus Rajewsky’s lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to ...

Researchers from Tokyo Metropolitan University in Japan on Saturday said they have found that the motion of unlabelled cells can be used to tell whether they are cancerous or healthy. They observed ...

This valuable study provides insights into a key question in comparative neuroanatomy and development. The authors provide evidence of the role for a particular micro-RNA in regulating the development ...

To test its effects, the team used a wide range of methods: biochemical assays, cryo-electron microscopy to visualize the binding site and performed studies in both patient-derived fibroblasts and ...