Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer's, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage ...

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Reduced levels of the TDP-43 protein have been linked to brain diseases like Alzheimer’s, frontotemporal dementia and ALS, ...

Surprisingly, the protein shortage primarily affects the brain's blood vessels. When endothelial cells lack enough TDP-43 protein, they don't stick together as tightly. This creates gaps in the ...

Erythritol, a sugar substitute often found in “sugar-free” or “healthy” foods and drinks, may not be as safe as many people ...

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A harmful form of the tau protein, which builds up in Alzheimer's disease and similar brain disorders, can directly damage ...

New research suggests that erythritol, a popular low-calorie sweetener, may impair blood vessel health by disrupting the ...

The team is also testing whether TDP-43 disfunction may spread between the endothelium and other cells in the brain. Brain blood vessels are in constant contact with neurons and support cells like ...