Early fruit ripening is a valuable trait for grape cultivation, but the underlying epigenetic mechanisms have remained ...

Unlike chemical-based methods such as bisulfite or TAPS sequencing, which degrade DNA and diminish phasing and structural context, PacBio’s native detection maintains DNA integrity and supports ...

Unlike chemical-based methods such as bisulfite or TAPS sequencing, which degrade DNA and diminish phasing and structural context, PacBio's native detection maintains DNA integrity and supports ...

Unlike chemical-based methods such as bisulfite or TAPS sequencing, which degrade DNA and diminish phasing and structural context, PacBio’s native detection maintains DNA integrity and supports ...

This study, however, takes a different approach. The researchers used buccal swabs (cells from inside the cheek) from 100 individuals between ages 7 and 84 and applied targeted bisulfite sequencing ...

However, more research is needed to fully unlock the clinical potential of DNA methylation. Targeted approaches such as reduced representation bisulfite sequencing (RRBS), microarrays, and ...

Recent findings link DNA methylation entropy to chronological age, offering insights into epigenetic changes that could ...

Importantly, all studies reporting on actual transcript numbers that were m5C-modified relied on RNA bisulfite sequencing, an NGS-based method, that can discriminate between methylated and ...