Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease ...

Gene transcription is a key component of the central dogma of molecular biology, which describes the flow of genetic information within a biological system. The central dogma states that DNA is ...

Transcription initiation and elongation of HIV-1 are critical processes regulating viral latency and activation. Despite these two processes playing essential roles in HIV-1 gene expression, how ...

Based on these findings, we designed and synthesized a new class of sequence-specific, synthetic transcription elongation factors (Syn-TEFs). These molecules are composed of programmable DNA-binding ...