One, dubbed the "sense" strand, carries genetic information. The other, the antisense strand, says nothing. In theory, scientists can use antisense molecules to block the production of a particular ...

"Making therapeutic sense of antisense oligonucleotides." ScienceDaily. ScienceDaily, 5 January 2021. <www.sciencedaily.com / releases / 2021 / 01 / 210105095623.htm>.

Critical milestones recently achieved by EnPlusOne, some of which were disclosed in a presentation at the TIDES 2024 conference, include: Synthesis of Leqvio® Antisense Strand ...

DNA/DNA double-stranded oligonucleotide is a new concept of oligonucleotide consisting of DNA-based antisense oligonucleotide and DNA-based complementary strand.

Researchers from Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, USA, report a modification wherein replacing the RNA strand of a heteroduplex oligonucleotide with DNA may ...

Antisense oligonucleotide (ASO) therapy has the potential to ameliorate many neurodegenerative diseases at the genetic level to suppress the production of harmful proteins or non-coding RNAs.

Alloy Therapeutics Announces a Target Specific Collaboration and License Agreement for use of AntiClastic™ Antisense Platform with Sanofi January 07, 2025 10:00 AM Eastern Standard Time ...