What is the significance of MSSA or MRSE with a vancomycin MIC of 2.0 mg/l? Was there enough data to support the area under the curve/MIC target and inferred troughs recommended in the guidelines?
Waite, Pharm.D; Donald P. Alexander, Pharm.D; C. Andrew DeRyke, Pharm.D Despite the higher frequency of target vancomycin troughs among patients dosed according to the revised protocol ...
Similarly, a pediatric study showed that ARC was associated with lower initial vancomycin trough levels in children treated for suspected sepsis, raising concerns about the risk of treatment ...
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