Tertiary amines, made of a nitrogen bound to three carbons, occur frequently in drug structures but are complicated to make. Synthesis often requires multiple steps under different reaction conditions ...

Shenzhen Salubris Pharmaceuticals Co. Ltd. has described tertiary amine compounds reported to be useful for the treatment of stroke, atherosclerosis, thrombosis, coronary heart disease and aortic ...

Chemists have found a way to apply a "foundational reaction" of organic chemistry to a stubborn class of chemicals, in a transformation that has been thought impossible for a century. Chemists at The ...

Emerging contaminants (ECs) including pharmaceuticals (PhCs), endocrine disrupting chemicals (EDCs), benzotriazoles (BTRs), benzothiazoles (BTHs) and perfluorinated compounds (PFCs), pose a potential ...

Some alcohols can't be made in a way that controls the crucial arrangement of chemical groups in the molecule. A reaction that uses common laboratory reagents offers a practical route to these ...

Organosulfur compounds play key roles in many biological structures and functions: two of the 21 proteinogenic amino acids contain sulfur, and seven of the 10 best-selling drugs in the US in 2009 were ...

LA JOLLA, CA – September 11, 2013 – Chemists at The Scripps Research Institute (TSRI) have found a way to apply a "foundational reaction" of organic chemistry to a stubborn class of chemicals, in a ...

IT has been found that, when compounds with local anæsthetic action containing tertiary nitrogen and belonging to different types of compounds are transformed into alkyl-, but especially into aralkyl- ...