Greedy accumulation-directed evolution generated multi-site combinatorial mutants of T7 RNA polymerase (T7 RNAP), breaking through the thermal stability barrier.​ ...

Post this CleanScribe RNA Polymerase is a novel DNA-dependent RNA polymerase that catalyzes the in vitro transcription (IVT) of a recombinant gene regulated by the T7 promoter.

The researchers have now created a mirror version of T7 RNA polymerase, a highly efficient enzyme that uses more convenient double-stranded mirror DNA templates. Weighing in at 100 kDa, mirror T7 ...

Rather than tackling the entire protein synthesis machinery, the authors zoned in on one critical member: the T7 RNA polymerase. The darling of the synthetic biology sphere, this enzyme is a hefty ...

“The T7 RNA Polymerase is the critical enzyme in the manufacturing process, making it a vital asset in support of our mRNA manufacturing service offering.