A man was shot at while driving on Interstate 64 in St. Louis County on Feb. 5. According to police, the man was shot at when ...

ST. LOUIS — Police are investigating a deadly wrong-way crash that happened early Friday morning on Interstate 64 near downtown St. Louis. According to the St. Louis Metropolitan Police ...

EAST ST. LOUIS The Illinois Department of Transportation today announced that a lighting improvement project on Interstate 55 ...

ST. LOUIS — Authorities have identified Alexander Whalen, 29, as a driver killed in a wrong-way collision on Interstate 64 last week when a pickup truck traveling in the wrong direction struck ...

One person was left injured Wednesday morning after a vehicle was partially trapped underneath a tractor trailer that had rolled over on Interstate 64 in Fairview ...

A women's apparel and home goods retailer is relocating its St. Louis-area store. Anthropologie will open a new location at ...

Cancel anytime. ST. LOUIS — A man died early Friday after his car was hit by a wrong-way driver on Interstate 64 in St. Louis. The crash was about 1:45 a.m. on westbound I-64 near South ...

If you use I-255 to get to Interstate 64 on the way to downtown St. Louis, you need a new route. The best alternate routes are Illinois Route 3 to the west and Route 157 to navigate around the ...

CHESTERFIELD — The state of Missouri has acquired a Chesterfield office as part of its effort consolidate its St. Louis-area ... adjacent garage, off Interstate 64 and Timberlake Manor Parkway.

At least 8in of snow was expected as the National Weather Service issued winter storm warnings from Kansas and Missouri to New Jersey.