Because RNAs are so central to our biology, they are also drivers of a wide array of diseases. Defects in how RNA is produced ...

Drug delivery technologies designed to protect and control the biodistribution of the active biologic or small molecule are driving ... delivery technology for RNA medicines.

Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny ...

Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny ...

These therapies can specifically target disease-causing genes or proteins, offering a precise and potentially safer alternative to traditional small-molecule drugs. Changes in RNA expression levels ...

Scientists found that pseudouridine helps small RNAs pass on traits and avoid immune detection, offering clues for future RNA ...

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight. Kamal is a freelance science journalist based in the UK with a PhD in virology ...

Ono Pharmaceutical Co. Ltd. has entered into a drug discovery collaboration agreement with Reborna Biosciences Inc. to generate RNA-targeting novel small molecules in the field of the central nervous ...

In addition, approximately 85% of proteins lack specific clefts and pockets for small molecule binding. Since many proteins have similar structures, it is also not always easy to target a single ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure ... Strategies such as tRNA supplementation, antisense oligonucleotide, and small molecule modulators of tRNA ...

Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, inside plant cells using a technique that results in a visible fluorescent ...

To achieve this, the researchers designed a small ribozyme-based RNA molecule (also called catalytic RNA) that attached a unique barcode to 16S rRNA upon gene transfer. This cat-RNA was introduced ...