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A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.
It occurs down a concentration gradient - molecules move from an area of high to lower concentration. This does not require a supply of energy because diffusion is a spontaneous process.
Diffusion is the net movement of molecules from an area where they are at a higher concentration to areas where they are at a lower concentration. This is due to the random movement of the molecules.
The previous theory that the blood–brain barrier (BBB) is a passive impermeable barrier ... to a lack of fenestration and reduce the diffusion of molecules across the vessels.
A new strategy for delivering bulky PROTACs to cancerous cells successfully utilizes the CD36 protein pathway on cells’ surfaces.