“When they transferred the tissue into a young ovarian environment, the stem cells woke back up and, lo and behold, a new population of oocytes formed,” says Tilly.

A critical role for N-cadherin in ovarian follicular development and ovulation is demonstrated with inhibitors or knockout of N-cadherin shown to inhibit ovulation by blocking mechanotransduction of ...

Ovarian stimulation uses hormonal medication to stimulate the ovaries to release a larger number of oocytes than normal, in order to provide enough good quality oocytes for fertilisation in vitro.

Researchers build ‘artificial ovary' to develop oocytes into mature human eggsResearchers at Brown University and Women & Infants Hospital of Rhode Island have built an artificial human ...

Melina Schuh has been fascinated with ovarian germ cells, or oocytes, since she began her graduate studies in 2004. “ [I] realized that only little was known about these important cells that are ...

Women with poor ovarian response to stimulation had higher likelihood of using frozen oocytes after planned cryopreservation vs. women normal response, particularly among women aged 30 to 39 years ...

Researchers at Brown University and Women & Infants Hospital of Rhode Island have built an artificial human ovary that can grow oocytes into mature human eggs in the laboratory. That development ...

This important study reports that two distinct waves of ovarian follicles contribute to oocyte production in mice. The paper provides large amounts of data that will benefit future studies, although ...

To create the ovary, the researchers at Brown University and Women & Infants Hospital formed honeycombs of theca cells, one of two key types of cells in the ovary, donated by reproductive-age (25 ...

The scaffolds were seeded with ovarian follicles - the spherical unit that contains a centralized oocyte with surrounding supportive, hormone-producing cells - to create the bioprosthesis.

The researchers xenotransplanted rat ovaries into renal capsules of immunodeficient mice. After transplantation, rat oocytes were retrieved from the mice, matured and fertilized in vitro.