A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses against metastatic pancreatic cancer.

A New Lipid Nanoparticle The mRNA COVID-19 vaccines, which have been crucial in saving lives, utilized specific lipid nanoparticles to deliver the mRNA. This new study paired mRNA with a single ...

However, LNPs consisting of helper lipids, PEGylated lipids and ionizable lipids can be susceptible to N-oxide-based impurities that can cause the loss of function of the genetic payload. To ensure ...

Specifically, I: (i) implemented a lipid-polymer nanoparticle platform for siRNA delivery to bone marrow endothelial cells in vivo to halt myeloma progression, (ii) developed the first-of-its-kind ...