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1st-of-its-kind database reveals how DNA mutations 'destabilize' proteins, triggering genetic disease
The researchers hope that the database will be used to develop new, personalized drugs that directly reverse the mutations' effects. The human genome carries instructions for at least 20,000 ...
Nature3y
Mutations Are the Raw Materials of Evolution
A mutation is a change in the sequence of an organism's DNA. What causes a mutation? Mutations can be caused by high-energy sources such as radiation or by chemicals in the environment. They can ...
New framework leverages 3D protein structures for systems-level analysis of cancer mutations
A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic ...