Researchers developed tubuloids from adult kidney cells. When exposed to cisplatin, the model replicated key steps in the chronic kidney disease progression, including DNA damage, cellular senescence, ...
This is the longest-lived set of developing kidney organoids derived from tissue stem cells The kidney developed over a half a year, enabling real-time observation, gene isolation for birth defects ...
A team defined key cells behind severe kidney damage in lupus. The research can inform future antibody therapies. A Berlin-led research team has uncovered critical regulators of severe kidney damage ...