Figure 1: Dnmt1 actively represses transcription using sequences that overlap the HRX repression domain. Figure 2: Dnmt1 686–812 represses transcription in a TSA-sensitive manner and has the ...

Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.

DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase ... The human Fallopian tube (FT) is ...