Furthermore, endoplasmic reticulum calcium depletion, the UPR, caspase-3 activation and apoptosis are markedly inhibited by selective inhibition of cholesterol trafficking to the endoplasmic ...

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes ...

Altered immunometabolism at the interface of increased endoplasmic reticulum (ER) stress in patients with type 2 diabetes. Journal of Leukocyte Biology, 2015; 98 (4): 615 DOI: 10.1189/jlb.3A1214-609R ...

We found that endoplasmic reticulum stress markers, activating transcription factor 6, inositol-requiring enzyme 1a, protein kinase RNA-like endoplasmic reticulum kinase, C/EBP homologous protein, and ...

Endoplasmic reticulum oxidoreductase 1 (ERO1) has traditionally been associated with proper protein folding in the endoplasmic reticulum, but it has recently been linked to platelet activation and ...

Christiane Hoffmann, Bartolome Plocharski, Ilka Haferkamp, Michaela Leroch, Ralph Ewald, Hermann Bauwe, Jan Riemer, Johannes M. Herrmann, H. Ekkehard Neuhaus, From Endoplasmic Reticulum to ...

Journal reference: Estébanez, B., et al. (2022) Resistance Training Modulates Reticulum Endoplasmic Stress, Independent of Oxidative and Inflammatory Responses, in Elderly People.

Insulin resistance is a hallmark of multiple metabolic disorders, including type 2 diabetes, obesity, metabolic syndrome, and polycystic ovary syndrome. It ...

Multi-color immunohistochemistry was used to identify the expression of ERO1A and define TME in patient samples. Results: Here, we show that ERO1A, an oxidoreductase involved in endoplasmic reticulum ...

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