Their paper is published in Molecular Psychiatry. The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates ...

The crucial final step yielding the desired product makes use of a decarboxylase enzyme. This particular enzyme has been evolved from naturally occuring microbial decarboxylases that depend on an ...

Figure 1: Interactions in the active site of AAD. It is disappointing that Westheimer's simple but elegant explanation for the decreased pK a of Lys115 is now recognized as incorrect. However ...

Selected plants were harvested at three stages of growth for analysis of the levels of four enzymes (aspartate and alanine aminotransferases, glutamic dehydrogenase and glutamic decarboxylase) and of ...

The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates receptors for the neurotransmitter glutamate ...