Researchers have systematically mapped the complex cellular pathways leading to glucocorticoid-induced osteonecrosis of the ...

Translational Therapeutics Open access Published: 05 April 2005 Indomethacin-induced activation of the death receptor-mediated apoptosis pathway circumvents acquired doxorubicin resistance in SCLC ...

Inhibition of caspase-8 abrogated these processes, suggesting that the death receptor pathway has a critical role in the apoptotic events induced by hispanolone derivatives.

The mechanisms behind NMDA-receptor-dependent apoptosis are unclear but seem to involve the release of apoptotic factors, for example, cytochrome C [34] from Ca 2+ loaded mitochondria, and the ...

The data suggests that amyloid-induced cell death is mediated by c-Jun, which in turn leads to activation of FasL and the apoptotic pathway. In support of this, cells carrying mutations in FasL, or ...

Cataracts are a leading cause of vision loss worldwide, and fibrosis-related complications after surgery often limit full ...

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This webinar will help you understand the link as well as differences between apoptosis and necroptosis. It will also introduce new tools developed to activate effectors of necroptosis. A live Q&A ...

Background. Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) has been shown to modulate multiple cellular processes, including apoptosis. The aim of this study was to assess the effects of HCV ...