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Forensic science has always relied heavily on the power of DNA to solve crimes, establish identities, and uncover hidden ...
Hypermethylation of CpG islands can cause tumors by shutting off tumor-suppressor genes. In fact, these types of changes may be more common in human cancer than DNA sequence mutations (Figure 2).
These modifications, which include DNA methylation ... For instance, abnormal CpG island hypermethylation is frequently observed in cancers and is often linked to tumor suppressor genes.