One of the major theories of aging, proposed by Harman in 1956, suggests that it is caused by the accumulation of oxidative damage affecting macromolecules, DNA, RNA and proteins, and possibly ...

In late 2021 a Russian-born billionaire named Yuri Milner gathered some of the most celebrated scientific minds of our time ...

Two major theories of aging both involve DNA, but in very different ways. Researchers have revealed that these theories may not be so different after all. Researchers at University of California ...

Harman hypothesized that these compounds, which chemists call free radicals, react with cellular components, causing damage that over time leads to aging. In the 1970s he expanded on this theory ...

A new research paper was published in Aging (Aging-US) on January 3, 2025, in Volume 17, Issue 1, titled "Characterization of DNA methylation clock algorithms applied to diverse tissue types." ...

NAD+ supports the repair of DNA damage caused by aging and environmental factors, helping to maintain healthier cells over time. By increasing NAD+ levels, NMN enhances mitochondrial function ...

SAN DIEGO — Scientists have long wondered what makes our bodies age. Is it like a car slowly breaking down from wear and tear? Or more like a computer whose programming gradually goes awry?

The way the body ages could be more resilient than previously thought, a new study suggests.

Their results suggest that DNA damage itself serves as the checkpoint, limiting the accumulation of genomic errors in cells during natural aging. The paper, published in Nature Communications ...

There are two prevailing theories about the relationship between aging and DNA. The somatic mutation theory suggests that aging is caused by the accumulation of mutations, permanent changes in our ...