In summary, these findings report the impact of chronic hyponatremia and its rapid correction on the microglia, further suggesting its contribution to hyponatremia-induced neuronal dysfunctions.

Chronic Hyponatremia Potentiates Innate Anxiety-Like Behaviors Through the Dysfunction of Monoaminergic Neurons in Mice. Molecular Neurobiology. doi.org/10.1007/s12035-025-05024-y.

In summary, these findings report the impact of chronic hyponatremia and its rapid correction on the microglia, further suggesting its contribution to hyponatremia-induced neuronal dysfunctions.

We first must exclude adrenal insufficiency, hypothyroidism, chronic kidney disease, and the use of thiazides. After excluding these etiologies, we must check the renal response.