The Wnt signaling pathway, a system present in living organisms, plays a pivotal role in cell growth, differentiation, and migration. It has a long history dating back to 1982 when the first Wnt ...

The canonical Wnt signaling pathway. The left panel (A) demonstrates the activated Wnt signaling cascade, while the right side portrays the inhibited Wnt signaling cascade. Wnt binds to the Fz ...

In MSI patients, the canonical Wnt signaling pathway was notably suppressed, resulting in the diminished expression of the mismatch repair enzyme, MLH1.

Through both in vitro and in vivo experiments, the research team examined how LGK974 affects bone formation and the Wnt/β-catenin signaling pathway.

Using the Western clawed frog Xenopus tropicalis as a model, we are investigating the roles of several genes and signaling pathways, including the AKT and canonical Wnt pathways, in inducing neural ...