Reference Ron R, Martínez-Sanz J, Herrera S, et al. CD4/CD8 ratio and CD8+ T-cell count as prognostic markers for non-AIDS mortality in people living with HIV. A systematic review and meta-analysis.

Killer immune cells destroy cancer cells and cells infected by virus. These CD8 + T cells are activated after detection of ...

The molecular markers CD4 and CD8—defining helper T cells and killer T cells, respectively—were once considered mutually exclusive. But "double positive" CD4+-CD8+ T cells have lately been ...

He, X. et al. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 433, 826–833 (2005). Article CAS Google Scholar Download references ...

As reported earlier, a chemotherapy regimen that consisted of dacarbazine, vincristine, lomustine, and bleomycin (DOBC) combined with natural leukocyte interferon (IFN) has been administered with ...

The 'choice' between the CD4+CD8− and CD4−CD8+ T cell lineage involves genomic specification via a set of transcription factors. A new study shows that the zinc-finger protein MAZR is another ...

The study, conducted by Dr Laurent Houcqueloux of Orléans Hospital in France, assessed measures of HIV DNA and the normalisation of the CD4 cell count and the CD4/CD8 ratio in people who started HIV ...

Res. 197, 161-169, 1988) showed that most of the colonies consisted of lymphocytes bearing CD4 or CD8 antigens. Since the fraction of CD4+ and CD8+ cells in PBL differs among individuals, we suspected ...

A new study has found that RA-associated lung disease is different from idiopathic pulmonary fibrosis. Researchers say their findings highlight the importance of CD4+ T cells, which may have ...

RESULTS: Patients not receiving lymphocyte reinfusion had a very slow recovery of lymphocytes. In particular, CD4 counts remained low (< 200/μL for 9 months). Lymphocyte reinfusion had a significant ...

To examine the Mettl3-dependent epi-transcriptional regulation in effector CD8 T cells, this study combined transcriptome and m 6 A modification abundance analysis of effector CD8 T cells. The ...