The largest “chunk” of the human genome, chromosome 1, is made up of 249 million base pairs (the rungs on the twisted ladder of the DNA molecule). Each base pair is made of two bases: either ...

In a recent review published in Science Bulletin, Professor Chen-Yu Zhang’s group at Nanjing University introduced the ...

We live in an exciting time for the RNA research community. Throughout the latter half of the 20th century, we believed that RNA’s primary role was to intermediate between DNA and protein. Over the ...

"This knowledge is important for us to design new unnatural base pairs that can be used by host RNA polymerases." Story Source: Materials provided by University of California - San Diego.

These Watson and Crick pairs always form in the same configurations: A-T and C-G. The double-helix structure of DNA is formed when many Watson and Crick base pairs come together.

But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, things are far more flexible, with many using RNA ...

At top, a DNA fragment 156 base pairs in length is in its most compact form, coiled 1.6 times around an eight-unit histone protein core. Next, a moderate stretching force releases 76 base pairs of ...

In a final twist, it turns out that a key ingredient in the formation of one-ringed bases was a liquid with a boiling point more than twice that of water's. As the reaction dried out, the liquid ...