However, unlike acromegaly, gigantism begins during childhood ... In patients who have a small pituitary gland tumor that can be removed via surgery, the disease can be cured 85% of the time.

In rare instances, acromegaly may be inherited, either as part of multiple endocrine neoplasia type 1 or as familial isolated pituitary adenoma. Recent studies “have identified a few families ...

Moreover, a recurrent missense mutation (p.E308D) has been found in some acromegaly patients ... Its expression in the hypothalamus and the pituitary gland, and its role in determining gigantism, ...

A new study demonstrates that a benign growth on the pituitary gland causing a growth disorder called acromegaly, which in some cases may lead to gigantism, are often inherited in Northern Ireland. A ...