In 1964, researchers first discovered the acetylation of histones. Subsequent studies revealed that not only histones but also numerous non-histone proteins are subject to acetylation ...

Researchers developed a cost-effective assay to be used with chemicals and potential carcinogens associated with reversible ...

Histones not only keep DNA organized ... transcriptional activation was associated with methylation at K4, which paralleled acetylation of K9 and K14, while transcriptionally inactive chromatin ...

How alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study ...

In a promising development for individuals with autism and intellectual disabilities, researchers from the Jawaharlal Nehru ...

Another important epigenetic modification is histone acetylation. Histones are proteins that help DNA fold. Acetylation makes histones more active, which also improves memory. The researchers tested ...

Researchers from Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), an autonomous institute of the Department ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Kundu and James Clement discovered that the brain represses the acetylation of DNA-associated proteins, histones, or proteins that give chromosomes structural support in mice with a mutated syngap ...

the acetylation of DNA-associated proteins, histones or proteins that provide structural support for chromosomes is repressed in the brain. “The epigenetic enzyme behind this acetylation seems ...