Newsweek Sports' expert predictions for Detroit Lions vs. San Francisco 49ers on Monday Night Football Week 17.

It’s 49ers vs Lions in Week 17 of the 2024 NFL season. Here’s how to watch, including time, channel, TV schedule and streaming info.

So, it’s come to this: no matter what the Detroit Lions do on Monday night in Week 17 against the San Francisco 49ers, they’ll be playing for the NFC North title against the Minnesota Vikings on Sunday night later this week, per the NFL schedule for Week 18. That also means the winner gets the No. 1 seed and an all-important bye week.

The Detroit Lions seek revenge and the NFC’s No. 1 seed as they travel to San Francisco for a “Monday Night Football” date with the 49ers.

The 49ers’ offensive line and running backs are incredibly banged up. That makes life difficult for San Francisco quarterback Brock Purdy. While the Lions are dealing with their own rash of injuries, Jared Goff and Detroit deliver and exact revenge in a game where they have much more at stake.

Charvarius Ward will join the list of 49ers missing Monday night’s game against the Lions at Levi’s Stadium after the team ruled him out Sunday afternoon. The veteran cornerback and his girlfriend, Monique Cook,

Brock Purdy loves playing on Monday Night Football, but the San Francisco 49ers have been reduced to nothing more than a spoiler role. Also, they received news that Charvarius Ward will miss the game against the Lions because of the expected birth of his son.

The San Francisco 49ers announced that cornerback Charvarius Ward was officially ruled out for Monday night’s game against the Detroit Lions. Ward was downgraded to out, but it wasn’t due to an injury.