"We are finding the 3D structure of the genome," said Satoshi Namekawa, professor of microbiology and molecular genetics at the University of California, Davis and senior author on one of the papers.

Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...

Three-dimensional genome maps are leading to a deeper understanding of how the genome’s form influences its function. A series of rodent experiments showed that even with abundant food and water, ...

Determining the 3D structure of the genome reveals spatial interactions between chromosomal regions. This crucial information can be used for genome scaffolding or for understanding how chromosomal ...

Crick and Watson were trying to build a 3D model of the DNA molecule. But they were not the only ones working on finding its structure. They were competing with a team at King's College London ...

Eventually, the chromosome loses its original structure and genetic information to the ravages ... bunch of freeze-dried jerky in the lab and examined it to see how well the 3D genome architecture was ...

University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and protects replicating DNA in dividing cells.

Both single- and double-stranded DNA features interact with RAD52 and hold the structure in place, allowing the team to obtain a detailed 3D structure of the whole protein-DNA complex. Using ...