In the final game of Week 17, the San Francisco 49ers will play host to the Detroit Lions on "Monday Night Football." San ...

For the seventh time this season, the NFL has fined Detroit Lions safety Brian Branch $10,128.

SportsLine's model has simulated San Francisco vs. Detroit on Monday Night Football 10,000 times and revealed its MNF picks ...

Jared Goff threw three touchdown passes and the Detroit Lions tuned up for their Week 18 division showdown against Minnesota ...

The Detroit Lions continue to set franchise and league marks across the board. Their latest re-writing of the NFL history ...

SportsLine expert Jimmie Kaylor shares his Week 17 NFL DFS picks, stacks, sleepers, rankings, values, lineups and player pool ...

With the high-scoring contest against the 49ers, the Lions clinched their fifth game this season with 40 points and 0 ...

The NFL Week 17 schedule concludes with a pair of high-profile NFC teams on Monday Night Football. The Detroit Lions at San ...

Lions vs. 49ers predictions and expert picks for Monday Night Football on December 30. Expect a big night from Jauan Jennings ...

The 49ers have nothing to play for other than pride at this point. They're facing a Lions team that has the best record in ...

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The record for most wins by a wild-card team will be reset as the loser of the Vikings-Lions game Sunday night will hold the new standard.